Behavioural Aspects of Marketing Essay Example | Topics and Well Written Essays - 2500 words

Behavioural Aspects of Marketing - Essay Example Even in the remote, unheard of societies, all people remain consumers with diverse interests and gullibility to get influenced in their decisions. Placing the consumers in the market place and psychologically dissecting their behaviour could be a cross-subject study of psychology, marketing and advertisement results. When we take consumers individually, it is necessary to take the perception and the factors influencing it. Learning and the resultant memory that motivates further action with changed or unchanged values that cause involvement and attitudes are very important. It is necessary to remember that this research region is very young, influx and energetic. It also is being 'constantly cross-fertilised' by external perspectives belonging to various disciplines. It is interesting to know the everyday activities of people. In one of the most influential works in the field, Solomon et al have impressively provided a comprehensive and contemporary detail of the currently prevalent consumer behaviour. The arguments are lively and practical while portraying the strategic marketing issues, diverse European values etc. They also provide a peek into the multi-dimensional European lifestyle, buying habits, marketing behaviour, their relationship with the global market and the behavioural fluctuations. They wrote in the preface: "The field of consumer behaviour is, to us, the study of how the world is influenced by the action of marketers. We're fortunate enough to be teachers and researchers whose work allows us to study consumers". This consumer behavioural insight has to be applied to our Whole Foods Market. USUAL BEHAVIOUR OF CONSUMERS The advertisements are so persuasive today that it is impossible not to listen or get influenced. Marketing opportunities, to a large extent are connected with the cultural dimensions that influence the behaviour issues and concepts. This does not mean that cultural compulsions do not change at all. We have seen that even in the rigidly religious countries, where almost everything is a taboo, consumer behaviour changes, but changes with ultimate slowness. Consumers are eager to new experiences, especially in the food region, with the recent food and nutrition knowledge. Solomon et al have drawn a multi-dimensional portrait of European consumers within which they have shown the European modern family structure and how it has influenced the household decision making. They have shown the traditional influence of the culture which still holds its own in addition to the influence and compulsions of income and the social class and how they command the consumer behaviour and individual decisions. Basic model of consumer decision making might follow the traditional path of problem recognition, search for the information, evaluation of alternatives, decision of choice, evaluation after the purchase and all these are adequately influenced or dictated by the values, lifestyle, cultural and cross-cultural differences. Habit forming products, non-habit forming products that are not purchased regularly fall into two different categories and are not influenced by the same decision making process. Then comes the power of

Cost and Benefits of Internal Recruitment for ACE Media Group Essay

Cost and Benefits of Internal Recruitment for ACE Media Group - Essay Example ACE Media Group will also save training and recruitment costs as the employee recruited will not need intensive training to perform his or her duties as a project lead in Malaysia. The director will only need to acclimatize to the foreign business environment but will not struggle to acquaint himself with the policies of the firm. The approach is also beneficial to the organization as it is much easier. The HR recruitment team will have access to sufficient information on potential candidates from its various branches across the world such as Sydney, UK, France Singapore and China. The availability of the information pool will make the selection process easier. In addition, internal recruitment will also facilitate succession planning. ACE Media group will incur several costs associated with internal recruitment. First, they would bear the opportunity costs linked to recruiting old talent who lack new perspectives acquired from outside the organization. Being that ACE Media Group is a big business, it is possible that internal politics will arise among interests groups, and this may jeopardize the unity of workers. Internal recruitment may not help in turning the company around as the recruited employee will tend to stick to the usual strategies and stale ideas due to inbreeding within the firm. External recruitment may bring to the company a new employee possibly a Malaysian who may not facilitate quick settlement in the foreign market due to local politics and prejudice.

5 Concepts Associated With Nutritional Health Health Essay

5 Concepts Associated With Nutritional Health Health Essay This is the type of malnutrition where there are more nutrients than are required for normal growth in a persons body. Thus, with the person taking in over nutrients, this means that he/she will be more likely to become overweight the fact that the foods that this person takes in are highly in caloric content. Over weight This is the enhanced body weight of the person in relation to his/ her weight. Hence, with the person being overweight, this means that this person is most likely to get coronary heart disease, stroke, and gall bladder disease and pregnancy complications. Therefore, a person to lower the risk of getting health problems due to being overweight, the person needs to make sure that he/she loses weight by doing regular exercise and eating healthy. obesity This is when a person has extremely high amount of body fat that is unhealthy. For that reason, with the person being obese, this person is also most likely to have serious medical conditions such as high blood pressure, diabetes, cancer, breathing problems, heart disease and stroke. Body mass index This calculates an individuals weight in relation to their height. It is very important that a person carries out BMI as he/she will be able to know whether he is overweight or not. Dietary reference values This gets to record the recommended nutritional intakes for UK population. Withal, the dietary reference values help to calculate approximately the amount of energy and nutrients needed by different groups of healthy people in UK population. P2 Describe the characteristics of nutrients and their benefits to the body. The kinds of nutrients which can be found in the persons body, these include of carbohydrates, proteins, fats, fibre, vitamins and minerals. Carbohydrates The characteristics of carbohydrates are that there are two different types of carbohydrates and these are monosaccharide and polysaccharide. Monosaccharide these are simple carbohydrates composed of one sugar molecule such as glucose and fructose. Whilst, polysaccharide these are carbohydrates made up of a long chain of simple sugar molecules that are joined together. The examples of polysaccharide carbohydrates these can be starch and cellulose. The benefits of carbohydrates to the persons body, they help to provide energy. Hence, this energy has to be broken down into glucose before cells can use it. In addition, carbohydrates are the bodys main source of fuel because when the person takes the right carbohydrates, this means that the persons body systems and organs will be able to function properly. The foods that can be found in Carbohydrates can be as such as whole grain cereals, fruits, beans, vegetables and dairy products. Proteins When it comes to the characteristics of proteins, these are large, complex molecules that have a variety of functions in the body and are essential to good health. There are two types of proteins and these are amino acids and peptides. The amino acids these are building blocks of the bodys proteins. Hence, some amino acids are produced by a persons body and other amino acids come from a persons diet. On the other hand, peptides these are two or more amino acids that are connected together. Hence, the proteins are made up multiple peptides. However, the benefits of proteins to the body, proteins help to build and repair tissues in the body. In addition, the proteins help to also make haemoglobin which is the part of the red blood cells that carry oxygen to all the parts of the body, make enzymes, hormones and also act as the building block of bones, muscles and blood. Lastly the examples of food that is highly in proteins this can be as such as diary products, meat, chicken, fish, beans, nuts and seeds. Fats Fat consist of saturated fat and unsaturated fats. The saturated fat can be as such as butter and cheese whilst unsaturated fat can be olive oil and sunflower oil. The benefits of fats to the body, is that the body needs fats to work properly by protecting the organs. The fats also help to provide energy in the form of calories, to absorb certain vitamins, to produce cell membranes, enzymes, neurotransmitters and lastly to produce hormones. The examples of foods that can be found in fats, these are eggs, butter, dairy products, margarine, cheese, olive oil, fatty beef and fish. Therefore, a person having food that contains fats, these foods will help to play a vital role in their body. Fibre The main function of fibre is to keep the digestive system healthy and also to function properly. Hence, fibre it helps to speed up excretion of waste and toxins from the body. However, it is advised that if a person is going to increase the amount of fibre in his/her diet, he should drink high levels of water so that the fibre can get absorbed. As a result, this will avoid a person from being constipated. The characteristics of fibre is that all the food that are rich in fibre such as fruits, wholemeal bread, porridge and cereals can fill up someone very quickly thus this will prevent someone from overeating. Additionally, the foods that are also rich in fibre are low in fat and calories as well as they slow down the digestion so they would not make a person to put on weight. Vitamins These are organic compound required as a nutrient in tiny amounts by an organism. A person taking the right vitamins through their diet, the vitamins will help them to maintain a healthy body and normal growth. The vitamins also help to serve vital functions in body processes such as the immune and nervous system. Therefore, its essential that a person takes food that is rich in vitamins. Nevertheless, the characteristics of vitamins is that every vitamin has a special role to play within the body that they help to regulate the processes such as cell growth and repair, reproduction and digestion. Furthermore, they are two types of vitamins and these are water soluble vitamins and fat soluble vitamins. When it comes to water soluble vitamins, these include of vitamin B1, vitamin B12, vitamin B6, vitamin C, vitamin B2. The water soluble vitamins might be as such as grains, fruits, vegetables, meat, eggs, nuts and milk. However, when it comes to fat soluble vitamins these consist of vitamins A, D, E and K hence these vitamins are stored in liver and fatty tissues. The food that can be found in these fat soluble vitamins can be such as vegetables cheese, whole milk, fish oil, and egg York. Minerals Its very essential that a person takes minerals in his/her diet. This is because these minerals help to control body fluids inside and outside the cells. The minerals also build strong bones and teeth as well as turn the food into energy. Withal, the most important minerals are iron, potassium, sodium and calcium thus these minerals can be found in foods such as cereals, meat, fish, vegetables and fruits. M1 Discuss similarities and differences in the nutritional and energy requirements of two groups of individuals. The two groups of individuals that I have decided to pick is the teenage girl that is 16 years old and of a pregnant woman. The differences between the teenage girl and a pregnant woman, when it comes to their nutritional and energy requirements is that the girl who is 16years of age needs to have 1800 calories per day whilst a pregnant woman needs to have 350 calories per day. In addition, the teenage girl needs these calories as shes stilling growing up and developing. For that reason, it is advised that this teenager needs to make sure that she understands her nutritional and caloric intake needs, as this will affect her physically in terms of being healthy. It will also prevent her from being at risk of getting healthy problems such as becoming overweight is shes taking in a lot of calories that she shouldnt . However, when it comes to a pregnant woman she needs fewer calories compared to a teenager as she needs to maintain her pregnancy weight as well as keep her energy up. Withal, the pregnant woman needs to make sure that she eats well during her pregnancy and also choose high quality food that is rich in baby building nutrients. Thus, with the pregnant woman eating healthy food, this will affect her unborn child physically that by the time she gets to give birth, her baby will look healthy. All the same, when it comes to the similarities between the teenager and the pregnant woman is that they both need to take in the right calories as this will affect them physically in terms of their health. With the teenager and the pregnant woman taking in the right nutrients they will be unlikely to be at risk of getting health problems such as becoming overweight, getting heart disease, high blood pressure or diabetes. Additionally, both the teenager and pregnant woman also need to eat the right food which is rich in all the nutrients. For instance the nutrients can be as such carbohydrates and fats hence these nutrients will help provide the teenager and the pregnant woman with energy. The foods can be such as whole grain cereals, fruits, beans, vegetables and dairy products. However, with the teenager and the pregnant woman eating these foods they will have to make sure that they do some physical activity such as going to the gym, taking a walk so that they could maintain their weight as well avoid getting healthy problems. When it comes to the differences between the teenager and a pregnant woman is that the teenager needs to limit her intake of solid fats like butter whereby she gets to avoid the chance of getting health problems which might affect her physically. Therefore, the daily recommended amount of oils that a girl who is 16 years old should be taking is 5 tea spoons. On the other hand, when it comes to a pregnant woman, she needs to take omega 3 which can be found from fats such as tuna and salmon. As a result, with the pregnant woman taking the omega 3, this will help her fetus to develop as it uses much of the fatty oils in a womans system. TASK 2 P3 Using a table, explain six possible influences on dietary intake. DIETARY INTAKE EXPLANATION Lifestyles The lifestyle can be a very vital influence on the dietary intake of a person depending on how the person lives such as being wealthy or poor. Religion Religion can influence on the dietary intake of a person the fact that some religions are not allowed to eat certain foods. Culture Culture can influence on dietary intake on someones choice of food and the way the person prepares the food. Finance This is essential influence on the dietary intake of a person. For instance if the person has got no problem with money, this means that this person will be more likely to provide him/herself with the foods that are rich in nutrients hence, this will affect him physically. Diet Diet is a vital influence on the dietary intake the fact that with the person taking the right diet, he will be unlikely to be at risk of getting health problems. Personal influence The person having a personal influence this will influence on the dietary intake of this person. For instance, with the person knowing that having the right diet is good for his health, he will be most likely to keep on having the right foods that are found in the basic nutrients. M2 Select three influences on dietary intake from P3 and assess how they may affect the nutritional health of individuals. Religion Religion can affect the nutritional health of the individual the fact that some religions are not allowed to eat certain foods. Therefore, some of these foods that the people are not allowed to eat might be rich in nutrients. For example, the Buddhists are not allowed to eat meat and meat is one of the foods that are rich in proteins and vitamins. Withal, with the person not eating the food that is rich in proteins and vitamins, this will affect this individual physically the fact that the proteins help to build and repair tissues in the body. In addition, the proteins also help make haemoglobin which is the part of the red blood cells that carry oxygen to all the parts of the body, the proteins also make enzyme and hormones. When it comes to vitamins, these will also help to regulate the processes such as cell growth and repair, reproduction and digestion of an individual. Therefore, if this individual that is a Buddhist isnt allowed to have meat, then he has to make sure that he at least eats other foods which are rich in vitamins and proteins as this will affect his health physically. Diet Diet may affect the nutritional health of an individual if the person maintains what he/she eats and this is by making sure that this individual eats the right calories that are recommended. Moreover, the person knowing the nutrients and what foods are found in the nutrients, this means that this person will be able to have a healthy diet. However, if the person doesnt know the foods that are found in the nutrients, theres a chance that this persons health will be at risk despite of the fact he/she will be eating unhealthy food. As a result, this person will be most likely to get health problems such as heart disease/stroke, high blood pressure, diabetes and also become overweight. Lifestyle The lifestyle may affect the nutritional health of an individual depending on how they live. For instance, if the person is wealthy that means he/she will be able to provide himself with the basic food which is rich in nutrients. Whilst a person, that might be poor he/ she might find it very difficult to manage to get the food that is rich in nutrients. As a result, with the person not taking the right food that is rich or less in nutrients; this means that this person is more likely to get health problems such as malnutrition. Furthermore, the life style will also affect the nutritional health of an individual depending on what kind of habits that the individual has. For example, if the individual loves to eat a lot of junk food, its more likely that this will affect his health physically, whereby this individual will become overweight as well get health problems such as diabetes. For that reason, the individual not to be at risk of getting healthy problems, he/she will have to eat the food that is rich in nutrients so that he can be healthy. D1 Make realistic recommendations for minimizing negative influences on individuals in a specific health and social care setting. The health and social care setting that I decided to use is a school thus the recommendations that could minimise the negative influences these can be as such as introducing children to new healthy foods, stopping children from going out for lunch, children making health poster, children having packed lunch wit healthy snacks. Introducing children to new healthy foods Its very important that the school introduces children to new healthy foods as this will affect the childrens health physically. As a result, with the children being introduced to healthy foods, they will be less likely to be at risk of getting healthy problems such as becoming overweight or obese. Moreover, the healthy foods could be as such as healthy snacks which might include of fruits and nuts thus, with the children knowing the good healthy snacks this will help the children to take in the right healthy snacks that will be rich in minerals and vitamins. Withal, vitamins help to maintain a healthy and normal growth and minerals help to control body fluids inside and outside the cells as well as also build strong bones and teeth. For that reason, its recommended that the schools should introduce children to healthy foods as this will help to minimise negative influences ion individuals. Stopping children from going out for lunch The school should make sure that they stop children from going out for lunch the fact that if the children go out for lunch, this means that theres a high possibility that these children will be buying junk food. With the children buying junk food, this will be mostly to affect their health physically despite of the fact that junk food is not healthy. Thus, the children will be at risk of having health problems that they will become overweight /obese, have breathing problems and also become diabetic. Consequently, its very crucial that the school does not allow children to go out for lunch; therefore it is recommended that the schools should provide children with lunch meals that are rich in healthy nutrients as this will help to minimise the negative influences on individuals. Children making health poster With the children making health posters, this will be an effective way of minimising negative influences on individuals. This is because, with the children making health posters, the other children will be mostly to know and understand the benefits of having healthy food and what sorts of food are rich in nutrients. Withal, the children understanding the nutrients and having healthy food, this will be very advantageous to their health as they will be less likely to get any healthy problems. For that reason, its recommended that schools should try and make health posters for the children as this will affect the childrens health physically in terms of having normal growth and development. Children having packed lunch with healthy snacks With the children having packed lunch with healthy snacks, this will help to minimise the negative influences on the individuals. This is because with a child having a packed lunch that is rich in nutrients as well as with healthy snacks such as fruits; this will make a child to have a balanced diet. Hence, with a child having a balanced diet, its less likely for the child to become ill. For example, if the child takes healthy snacks this means that these snacks are rich in vitamins and minerals thus these nutrients help to maintain a healthy and normal growth. For that reason, its very essential that a child gets to have a healthy packed lunch with healthy snacks. Additionally, its also recommended that the school should also advise children to drink a lot of fluids and water as this will prevent the children from being dehydrated. Therefore it is recommended that the schools tell children to have healthy packed lunched with healthy snacks as this will help to minimise the negative influences. Advise children to take part in P.E The schools should advise children to take part in Physical exercise as this will benefit the children the fact that physical exercise will help them to control their weight, strengthen their bones and muscles, improve their mental health and mood as well reduce the risk of the children getting health problems such as overweight. For that reason, its recommended that the schools should always advise children to take part in P.E. TASK 3 P4 Use a table to summarise your one week quantitative analysis. DAY BREAKFAST LUNCH EVENING MEALS SNACKS ACTIVITY MONDAY Medium Banana (105cal) Potato Chips(487cal) chicken(431cal) 2 pieces 1 glass of water Rice(216cal) Beef(164cal) 1glass of water 100g bar Cadburys diary milk chocolate (520kcal) 1hr at the gym TUESDAY None Potato Chips(487cal) chicken(431cal) 2 pieces Spaghetti (220cal) 1 glass of water Cheese puffs twists (122kcal) A bar of snicker(319kcal) None WEDNESDAY Cornflakes (100kcal) 1 glass of water Lasagna(124cal) 1 glass of Apple juice (117kcal) Rice(216cal) 1 glass of Apple juice (117kcal) Banana chips (147kcal) 1 packet of walker crisp (187kcal) Cycle for 30mins THURSDAY None Spaghetti(220cal) 2 glasses of water Rice(216cal) chicken(431cal) 2 pieces 1 glass of Apple juice (117kcal) Kellogg cereal bar (370kcal) None FRIDAY None Shrimp(206cal), rice(216cal) 2 glasses of water Lasagna(124cal) Peas carrots (97kcal) 2 glass of water 100g bar Cadburys diary milk chocolate (520kcal) 1 packet of walker crisp (187kcal) None SATURDAY Medium Banana (105cal) 1 glass of water Fish(210cal) potato chips(487cal) 1 glass of Apple juice (117kcal) Lasagna(124cal) broccoli(35kcal) A glass of orange juice(88cal) Cheese puffs twists (122kcal) A twin bar of Twix(284kcal) Walk to the park for 15mins SUNDAY Weetabix (213cal) 1 glass of water Salmon(280cal) Rice(216cal) 1 glass of Apple juice (117kcal) Rice(216cal) Beef(164cal) A glass of orange juice(88kcal) A twin bar of Twix(284kcal) 1 packet of walker crisp (187kcal) None P5 Prepare a one week plan to improve the nutritional health of the chosen individual in P4. This information can be presented in the form of a table. DAY BREAKFAST LUNCH EVENING MEALS SNACKS ACTIVITY MONDAY Medium Banana (105kcal) 2 glasses of water Potato Chips(487kcal), broccoli(35kcal) chicken(431kcal) 2 pieces 1 glass of water 1 glass of Apple juice (117kcal) Rice(216kcal) Beef(164kcal) Peas carrots (97kcal) 2 glass of water Low fat Yogurt 100gms (112kcal) 1 bar of Dark chocolate (100kcal) 1hour at gym TUESDAY Apple juice 1 glass(117kcal) granny smith apple(45kcal) 2 glasses of water Potato Chips(487kcal) chicken(431cal) 2 pieces 2 glass of water Spaghetti (220kcal) coleslaw(79kcal) corn on cob(140kcal) 1 glass of Apple juice (117kcal) 1 packet of walker crisp (187kcal) Walk for 10mins WEDNESDAY Cornflakes (100kcal) Apple juice 1 glass(117kcal) 2 glasses of water Lasagna(124cal) Beef(164kcal) 1 serving of coleslaw(79kcal) Peas carrots (97kcal) A glass of orange juice(88cal) Salmon(280kcal) Rice(216kcal) broccoli(35kcal) corn on cob(140kcal) 1 glass of Apple juice (117kcal) Banana chips (147kcal) Low fat Yogurt 100gms (112kcal) 2hrs at gym THURSDAY Weetabix (213cal) 1 glass of Apple juice (117kcal) 2 glasses of water Spaghetti(220cal) 1 serving of coleslaw(79kcal) Cream cheese(137kcal) A glass of orange juice(88kcal) Rice(216kcal) chicken(431kcal) 2 pieces A glass of orange juice(88kcal) 1 apple and 1 pear (125kcal) Low fat Yogurt 100gms (112kcal) Walk to the dog park for 30mins FRIDAY Weetabix (213cal) 2 glasses of water Shrimp(206kcal), rice(216kcal), broccoli(35kcal) corn on cob(140kcal) 1 glass of Apple juice (117kcal) Lasagna(124kcal) fried noodles (43kcal) cauliflower (23kcal) 1 glass of Apple juice (117kcal) Avocado on toast 1 slice of bread(220kcal) Cycle for 30mins SATURDAY Medium Banana (105cal) 2 glasses of water Fish(210kcal), potato chips(487kcal) broccoli(35kcal) Apple juice 1 glass(117cal) Lasagna(124cal) Peas carrots (97kcal) 1 serving of coleslaw(79kcal) corn on cob(140kcal) Cheese puffs twists (122kcal) A twin bar of Twix(284kcal) Walk the dog to the park for 30mins SUNDAY Weetabix (213kcal) 2 glasses of water Salmon(280kcal) Rice(216kcal) cauliflower (23kcal) broccoli(35kcal) A glass of orange juice(88kcal) Rice(216kcal) Beef(164kcal) Peas carrots (97kcal) Apple juice 1 glass(117cal) 50g(1.8oz) reduced fat hummus with veggie sticks(125kcal) A teaspoon each of pumpkin seeds, sunflower seeds and raisins(240kcal) 2hrs at gym M3 Assess how the plan devised in P5 will meet the nutritional needs of the individual. The one week plan that I devised in P5 will help meet the nutritional needs of the individual the fact that, when I made another plan in P5 so that I could improve the nutritional content of the individual, I tried to make sure that at least I meant the daily calories that a person should have. Moreover, with the person not eating proper food or missing out meals, this will lead to reduced levels of blood sugar. For that reason, with the person having low levels of blood sugar, its most likely that this person will faint. Withal, the plan devised in P5 will help meet the nutritional needs of the individual as I had to make sure that in the plan, the person will have to have breakfast every day as this will affect this person physically. Thus, with the person taking breakfast every morning, she will be active and also be will have enough energy to carry out the tasks at work. Therefore, a person taking breakfast every morning is very crucial. Additionally, the plan I devised in P5, will definitely help the nutritional needs of the individual the fact that every meal that this person will be having, is rich in nutrients. For example, when it comes to lunch time and evening meals the person gets to have vegetables with her meals thus vegetables are rich in vitamins and minerals. Therefore, with the person taking vegetables that are rich in vitamins and minerals, this will affect this persons health physically as the vitamins and minerals they help to regulate the processes such as cell growth and repair, reproduction and digestion as well as control the body fluids that come in and out of the cells of this individual. Furthermore, the plan that I devised in P5, will also help the nutritional needs of the individual in spite of the fact that this person will now have to do some activity such as going to the gym, walk to the park and also do some cycling. As a result, this will affect this persons health that she will not be at the risk of getting healthy problems such as becoming overweight or obese. In addition, with the person also doing some activities such as going to the gym, this person will be able to burn off some of the calories, in case if this individuals calories were more than what she should have. Moreover, the plan that I devised in P5 will also help the nutritional needs of the individual the fact that this person will be drinking more water regularly. Hence, with the person drinking water every day its very vital as water makes up 70% of the human body and also it will prevent a person from being dehydrated. Additionally, with the person also drinking water, the water will help to transport oxygen and nutrients through the blood and water is a major component of every body cell, tissue and organ. Lastly, the plan that I devised in P5 will also help the nutritional needs of the individual as I had to make sure that this person at least this person gets to have some healthy snacks. Withal, the person having healthy snacks this will affect the persons health physically as the healthy snacks help to keep the energy levels up and also they help to keep an individual full throughout the day without overeating at meals. Furthermore, with the person having healthy snacks such as apples and bananas, these are rich in vitamin C hence; these fruits are important for the immune system, teeth and wound healing. D2 Evaluate how the nutritional plan might improve the health of the chosen individual in P4 and P5. When it comes to the nutritional plan I did in P4 and P5, this might help to improve the health of the chosen individual the fact that I tried to make sure that in both the plans I did in P4 and P5, this person did physical activity. Thus with the person doing activity, this will benefit this persons health physically as he/ she will be at less risk of getting any healthy problems. However, when it comes to the plan I did in P4, the person did less physical activity and this will be less effective to this individuals health as he/she will be at risk of getting health problems. On the other hand, when it came to the plan I did in P5 where I had to improve the plan from the one I done in P4, I made sure that this individual attended the gym more regularly, did some cycling and also walked the dog to the park. As a result, with this individual doing these different activities, this will be affect his/her health physically as it will help him/her to control his/her weight, strengthen her bones and muscles, improve her mental health and mood as well reduce the risk of her getting health problems such as becoming overweight, getting diabetes or cardiovascular disease. The nutritional plan that I did in P4, it will also help to improve the individuals health the fact that I tried to make sure that a person had water and other fluids such as apple and orange juice. However, in P5 I had to make sure that had to improve the plan had made in P4 because the person never had more fluids regularly. For that reason, with a person having less fluids in his diet this will affect this individuals health physically as theres a high possibility this individual will be more likely to be dehydrated and also become constipated. Therefore, it is very crucial that a person take fluids more regularly the fact these fluids are rich in minerals as well as vitamins. Moreover, with the person drinking water its very important as water makes up 70% of the human body and also it will prevent a person from being dehydrated. Hence, the water also helps to transport oxygen and nutrients through the blood. Withal, the nutritional plan of P4 and P5 will help to improve the health of an individual as its recommended that a person needs to drink water. As a result, in both my nutritional plans had to make sure that this person had 2litres of water but I never met the daily intake of the water that is meant to be taken by an individual the fact that in both my plans it was less than 2litres of water. When it comes to the nutritional plan that I did in P4, I mad

Nuclear Energy :: essays research papers

Nuclear energy by definition is the energy consumed or produced in modifying the composition of the atomic nucleus. Nuclear energy is used for things such as atomic bombs, hydrogen bombs and other nuclear weapons. Nuclear energy can also be used for powering electricity-generating plants all over the world. There are many arguments for and against nuclear power. Nuclear power is an inexpensive clean source of power. Others feel that because of the hazardous radiation emitted during the producing of the power and the radioactivity of the material used that nuclear power is not as good as the alternatives which are fossil fuels and solar power.(Hansen, 1993) If matter changes state or composition, it is accompanied by the production of energy. Processes such as combustion produce energy by rearranging the atoms or molecules of that substance.(Brain, 1998) An example of this is the combustion of methane (natural gas) CH(4) + 2O(2) = CO(2) + 2H(2)O + energy In this example the amount of energy released is eight electron volts or 8 eV. The electron volt unit is the unit used by nuclear physicists. The electron volt represents the gain in kinetic energy when an electron is accelerated through a potential drop of one volt.(Brain, 1998) The most common nuclear reaction is nuclear fission. Nuclear fission is the process in which a heavy nucleus combines with a neutron and separates the heavy nucleus into two lighter nuclei.(Roy, 1993) The most typical fission reaction is that of uranium-235 it is as follows: 92 U235 + 1 neutron = 38 Sr96 + 54 XE138 + 2 neutrons + energy Another type of nuclear reaction is nuclear fusion. Nuclear fusion occurs when two light elements combine to form a heavier atom.(Grisham, 1993) An example of this is: 1 H(2) + 1 H(3) = 2 He(4) +1 neutron + energy Nuclear Fission Nuclear fission is a complex process, but many products are formed during this process. Not only the two nuclei but also neutrons, beta particles, neutrinos and gamma rays are created during the fission process.(Roy, 1993) There are more than fifty different ways a nucleus may undergo fission. Some of the ways are much more common than others. During the fission process the nucleus breaks into to unequal parts, one lighter fragment and a heavier fragment. These nuclei are formed with excess energy that they do not usually have in their ground state they must lose the extra energy. They release this extra energy in the form of gamma radiation or sometimes neutron emission. The primary fragments are rich in neutrons and are radioactive. Uranium-235 which contains 92 protons and 143 neutrons are more likely to under go fission when bombarded by low-energy neutrons.(Hansen, 1993) Nuclear Fission Used in Bombs The fission process was discovered in the late

Market Background

Market segmentation is the process of â€Å"dividing a market into distinct groups of buyers who have distinct needs, characteristics or behavior and who might require separate product or marketing mixes† (Kotler, 2004). Underlying the decision to segment the market is the recognition that a single market is not composed of people with homogenous needs, attitudes amd behavior and therefore requires a different marketing strategy for each group of people. This process helps marketers in identifying opportunities for a new product or product mix by identifying specific needs of a group of consumer marketer (Kinsey, 2005) Market segmentation can be done in many ways. A company with a customer base over a large geographic area can divide its market into various geographic areas. It can also segment the market on the basis of demographic factors such as gender, age, family size or family life cycle stage, profession, education, ethnical background etc. Other techniques include psychographic segmentation is another type of segmentation that is â€Å"based on social class, lifestyle or personality characteristics† and behavioral segmentation that is â€Å"based on the consumer knowledge attitude, use or response to a product† (Kotler, 2004). Other than the geographic segmentation all the other segmentation techniques requires a lot of consumer research with a demographic research on a lesser extent. Whatever segmentation techniques are used the market segments identified must be measurable in terms of size, purchasing power etc, accessible through target marketing, substantial, differentiable so that they should deserve the investment in a separate marketing strategy and actionable that is creating a marketing strategy for it should be practically possible for the company (Kotler, 2004). The task at hand is to segment the beverage market, decide on the target market and then design the most effective product mix for that segment. The beverage under consideration has an ingredient that is perceived to have health advantages. Thus, the drink can be positioned to be a wholesome addition to a healthy diet. The fact that their competitors have limited themselves to athletic males has left most of the market open for new product. The company can market the product to a much larger psychographic segment which is of health conscious consumers. On a secondary level some demographic segmentation can be done where students and young professionals are targeted through relevant marketing strategies that promote the drink as a source of nutrients needed for mental and physical growth necessary to cope with a demanding environment. Also a market strategy can be designed such that it encourages product use n the morning with breakfast. This type of strategy comes in the occasion segmentation as part of the behavior segmentation. With a powerful promotion program the beverage can become a necessary morning drink for all health conscious people. As the product is being promoted as a health drink it should contain appropriate nuitrants and vitamins and fruit extracts whose details should be given on the package. As it is being promoted as a morning drink it should be light and should not have sharp taste or smell. Also along with individual packages it should be available in easy to open packages that contain at least seven servings. Kinsey, J & Yeap, C. (2005). Buyers and Market Segments: Food Marketing Economics. Presented at APEC 4451/5451 lecture at University of Minnesota

Block Scheduling vs Periods Essay

A small debate has always been discussed when talking about block scheduling and traditional class periods. Some people like the longer classes while others prefer the traditional six shorter class periods. Everyone has their own opinions about block scheduling. Block scheduling can be really helpful to high school students in many ways. Although, block scheduling is a longer time spent in one class, it should be mandatory in all high schools rather than traditional class periods. Block Scheduling is more like college classes, rather than traditional six period classes. There are many ways to schedule with using the block method. One option is the alternating block schedule. Classes meet each day for ninety minutes. Four classes meet on A days, and four meet on B days, with days of the week alternating as A or B. The second method is the semester block scheduling. This allows students to attend just four classes for ninety minutes each day for an entire semester. The following semester students enroll in another four classes. These two methods are the most like college classes. It is good for high school students to experience and get used to the longer time spent in classes to prepare them for college. Block scheduling allows students to take more subjects and cover more material in one class. High school students need to prepare for the future and get used to the way college classes are organized and with the block scheduling they are sure to do that. With the six traditional class periods students only have forty-five to sixty minutes in each class before the bell signals for the next. By the traditional six classes they stay in the same subject all year around. Block scheduling gives two more extra classes to take because of the extra time (Schroth). Many high school students are involved in extracurricular activities at the school they attend. By using the block method, teachers can get most of everything they had planned finished in one class allowing extra time to do class work and students will not have as much homework. Only having four classes cut down on homework rather than six classes all year around. Block scheduling allows teachers to teach less students and can have relationships and get to know each student very well. Students can get direct help from the instructor and can learn more easily (Ediger). This is good for at risk students because it gives them a chance to just focus on a few subjects each semester rather than all year long. In some schools, block scheduling allows students to take dual enrollment at their local community college. By doing this, high school students can get a head start on college classes if they are able (Childers). Many opportunities to help academics can come from the block scheduling method. Block Scheduling allows students who fail a subject the first semester, to retake it the second semester. Many schools have seen test scores increase (Wilson). While students have more time to do daily work instead of homework, teachers have more time for their planning period. It allows more time for more in class projects and individual work between students and the instructor. Many teachers have said that with block scheduling, more discipline problems have decreased. Because traditional scheduling requires changing classes six times a day, students get more chances to start trouble between those classes. With block scheduling you’re only changing three times and there is a less chance of problems between classes (Wilson). Block scheduling does have its disadvantages just like traditional scheduling. Since students will not be going to class daily, some subjects might require drill and practice to stay refreshed on a student’s mind (Schroth). With classes being ninety minutes, students might get tired or bored with the subject they are in and ready to go to the next class. A bad instructor could cause students to not want to go to class for that long of a time. Block scheduling advantages outweighs its disadvantage. It prepares high school students for college. College classes are completely different than high school. Teachers have more time to prepare, teach and individually help each student in class. Discipline issues have decreased because of the less time spent in the hallways. The block method is great for all high schools and preparing students for the future.

10 high-paying trucking jobs hiring right now

10 high-paying trucking jobs hiring right now Do you yearn to spend your days on the open road with nothing but your thoughts and the roar of the engine? Then you must be a born trucker. However, deciding to become a pro trucker is just the first set in the decision-making process. Now you have to decide what kind of trucker to be. After all, you’ll want to make sure you land in the right spot in this surprisingly complex industry so that you can maximize your earning potential and your job satisfaction. Here’s a list of some of the highest-paying trucking jobs out there right now.1. Tanker HaulerTanker trucks are those big machines that haul liquid such as water or gasoline. You’ll need to get your CDL endorsed to do this particular job, which can be both difficult and dangerous since liquid cargo can be unstable. However, it is one of the highest paying trucking jobs- fuel tanker drivers earn as much as $70,000 per year. Consider the extra training and certification as an investment in your career.2. Hazma t DiverLike tanker hauling, hauling hazardous materials is another way to up your game. Get your CDL endorsed for this skill and you can widely increase the number of tanker hauls you’re eligible to do. Endorsing your CDL means you have access to a specialized (and lucrative) category of jobs. Hazmat drivers are also guaranteed a minimum of $1,000 a week after a year of experience according to RoadMaster.com.3. Oversized Load HaulerYou need a special license and special training to haul extra large loads such as heavy machinery, but, again, driving wide or oversized loads will mean you’ll be paid more. According to WideLoadShipping.com, oversized load truckers earn between $53,125 and $90,000 on average. You might even earn six figures if you’re willing to sacrifice some home time and work extra hard.4. Ice Road TruckerWhen it comes to trucking, no one earns more than ice road truckers. These are the brave souls who deliver their loads over pure ice. It’s an extremely dangerous career, but it is also extremely well paid- AOL Jobs reports that some ice road truckers earn up to $250,000 for just two months of icy-season work.5. Transport DriverHauling junked cars, specialty vehicles, or luxury cars will earn you more than the standard cargo. Transport drivers earn about $53,000 a year on average.6. Team DriverTeam drivers hook up with others to go twice as far, twice as fast. You won’t get a lot of breaks outside of the truck in this field, but you will make amazing time- and money. The average team truck driver makes $50,000 per year.7. OTR DriverSpecialize in long hauls from coast to coast and you’ll be sure to earn a good living. OTR, or â€Å"Over the Road,† drivers do daunting work and must be 21 or older to score gigs, but at a starting annual salary of $40-45,000 per year according to RoadMaster.com, the pay is great.8. InstructorNot every job in the trucking industry involves actual trucking. Instructors t each others how to do this specialized work while still being able to go home every night. They earn between $22,500 and $51,800 a year according to PayScale.com.9. RecruiterIf you’d rather just get paid to send other guys out on the road, you should consider becoming a recruiter. According to GlassDoor.com, the national average salary is a very enticing $50,000 a year for this comparatively low-effort career.10. Owner/OperatorWould you rather be your own boss? Well, owning a trucking company may sound like a great job, though there are numerous expenses to consider. Nevertheless, you’re still likely to end up earning a lot more than the drivers who actually have to lug their loads across the country. Indeed.com estimates that the average owner/operator makes an average annual salary of $141,000. That’s not bad for playing with trucks!

How is the theme of redemption explored in A Christmas Carol Essays

How is the theme of redemption explored in A Christmas Carol Essays How is the theme of redemption explored in A Christmas Carol Paper How is the theme of redemption explored in A Christmas Carol Paper Essay Topic: A Christmas Carol A Christmas Carol was written by Charles Dickens in the mid nineteenth century depicting the social and economic life of the working people in London. The appalling conditions under which the people had to work is in sharp contrast with the ways the rich people lived in luxury. Most of the people, especially the poor, lived in a rejected environment and had to work long hours with little wages, thus enduring hardship. Children, as young as six, are made to work in order to support their families expenses. Although the rich people had a lot of money, they did not help the poor. They thought that people became poor because they were lazy and did not do enough work. Dickens chose to call his story a song because of the Christmas hymn, Tis season to be jolly. He wants us to remember the poor by giving and sharing in the special time of Christmas. He wants to express the spirit of Christmas from a Christians point of view. This includes hymns and charities as well as remembering the joyful time about the birth of Jesus Christ. Also, he wants us to know the meaning of true Christmas. Finally, Dickens chose the Christmas setting for his novel to help us explore the character of Scrooge. The novel consists of staves instead of chapters (a stave is a musical score). The different staves are like parts of the tune, which makes up the whole song, and the book is the song. This might be another reason why he chose this title. STAVE ONE, MARLEYS GHOST The main character in this book is called Ebenezer Scrooge. In the beginning of the book, this character arouses a curious ambiguity in the readers response towards him. In stave one itself, the writer promptly describes him as a tight-fisted hand at the grindstone, Scrooge! A squeezing, wrenching, grasping, scraping, clutching, covetous old sinner! Hard and sharp as flint, from which no steel had ever struck out generous fire; secret, and self-contained, and solitary as an oyster. His attitude is so bad that Even the blindmens dogs appeared to know him; and when they saw him coming on, will tug their owners into doorways and up courts; and then will wag their tails as though they said, No eye at all is better than an evil eye, dark master! This cold-blooded, miserly, rude, greedy and extremely selfish old man works in a counting house in London. Although he is rich, he is very tight with his money. He pays his employee, Bob Crachit, little wages and leaves the latter shivering in his office because he refuses to spend money on coal for a fire on anyone except himself. Moreover, he hates Christmas. Because of this, he is reluctant to give Mr Crachit a day off for Christmas. It shows how callous he is in ignoring basic rights for workers. He is also rude to his nephew, who comes to invite him to a Christmas dinner party. Scrooge refuses the invitation and calls Christmas a humbug. He then forces his nephew out of his office. His attitude towards the poor is also repulsive. He has no consideration for them. He treats them as a dozen of lazy people and wonders why he should provide for them. Scrooge looks down upon the charity collectors because he simply states that the poor should die because they are simply useless to the world. He argues that prisons are the only charities he cares to. Through Scrooges implicit defense of the poor laws, Dickens dismisses the excuses of the indifferent upper class as irresponsible, selfish and cruel. Dickens has used both simple and sophisticated language to present and develop Scrooges character. He uses anti-Christian terms whenever he has Scrooge speaking. For instance, he spits out an angry word Bah Humbug, in response to his nephews sincere merry Christmas. Also, when he enters his apartment after seeing Marleys ghost on the door knocker, he says, a disgusted Pooh-pooh! Even before the arrival of Marleys ghost, the atmosphere is fairly tense. Dickens describes Scrooge as a thoroughly unhappy person. Scrooge took his melancholy dinner in his usual melancholy tavern. This means that Scrooge is already in a low spirit. Scrooge then passes the yard, which the writer describes as, so dark, that even Scrooge who knew its every stone was afraid to grope with his hands, he then approaches the door of his apartment; there he suddenly comes face to face with Marley. At first, he could not believe his eyes and thinks it is some kind of hallucination. Can it really be Marley? But he is not dead as a door nail. When he enters his house, he checks the back of the door knocker, but could not find anything, apart from the bolts that held the door knocker in place. He shakes his head and runs up the stairs. He double locks his door to his room and is about to take the gruel for his cold. When, at that moment, he senses a chill blowing through the rooms and the papers start to fly around. His apartment is described as a gloomy suite of rooms which are old and dreary. The wind gets stronger, the clock strikes and the disused bell rings. The door to his room flings open, Marleys ghost, dressed in chains, appears and stood in front of him. Instantly, Scrooge receives a terrific shock and he screams. He kneels down before Marley and wants to know what the deceased has come here for. The arrival of Marleys ghost may scare young readers, but it definitely makes us realise that material wealth is not everything on earth, because it helps to increase our burden in the life thereafter, ( the life to come after resurrection ). This gives Scrooge a sense of realisation about his bad nature and persuades him to make a change before it is too late. Although Scrooge is dumbfounded with fear, this visit makes him think back of all the bad things he has done to the community.

Questions for a College Representative

Questions for a College Representative Are you wondering how you could start a conversation with a college representative? Here are some tips thatll help you have a productive conversation with your college representative. Lets get answers to your important questions. College Fair Topics and Questions Ideas First, its a good idea to write out a list of things that are important to you before you go. You shouldnt feel like you have strange priorities or weird questions. Maybe something off-beat is interesting to you. College representatives hear the same questions all the time, so theyll be glad to hear something new. If you wonder about LGBTQIA life on campus, the potential for racial tension, or if youre worried about spiders in the dorms, go ahead and ask about it. Start with Hello, how are you? or Hi, my name is ... for a relaxed beginning to your conversation.Try not to ask a vague question like Tell me about your college, since the representative will have no idea where to start. That can be frustrating for the college representative and the student because the conversation will have no direction.Be specific with questions by saying things like Tell me about class spirit or Can you give me examples of some campus traditions? instead. Questions phrased in such a way will give you a sense of the atmosphere and give the representative something specific to talk about.Ask for a list of majors that you could take with you. You could look over it later.Ask about the enrollment deadline and the recommendations for taking the SAT. Some colleges will need your scores earlier for admission considerations.Ask if subject scores (like SAT II Math or History) are required or recommended.Feel free to ask if the representative can waive your application fee , but know that this usually works best at private colleges. Ask if there are any scholarship secrets. There are many little-known tricks that differ from college to college, but the conversation doesnt always get around to this in a rushed environment like a college fair.You will want to know the admission requirements, of course. You may also want to ask whether admissions officers make decisions on numbers, or if they consider activities. Some colleges  go by scores and grades and follow a formula. Other colleges give greater weight to activities, experience, and interests.Ask if a student leader can contact you to give you a students perspective. If its possible, provide the representative an email address for this.Go ahead and ask about the food. Sometimes there are many choices, and other times there arent. Remember, youll have to live with it for four years.Ask how the food plan works.Find out the safety history of the campus and the surrounding town. Sometimes the campus rests in an area where theres a high crime rate just outside th e area considered the campus. A representative may not mention this. This is also something you should research on your own before you get too attached to the dream. Be safe! Ask how many of the students drop out, transfer away, or how many stay and graduate. College representatives may cringe at this one because student retention is a touchy issue at many colleges. A low retention rate may be a warning sign, though.Ask: Whats the biggest complaint from current students?Is tutoring available?If class size is important, ask about it. Keep in mind, however, that class sizes are less important when good individual tutoring is available.Find out if tutoring is free.Ask for a direct phone number for an admission counselor and a financial aid counselor to avoid getting caught up in an automated phone quagmire at some point. Smaller colleges will be happy to provide this, but larger colleges may not. Its always worth a try though.Find out if the administration listens to student concerns. This is one of the things you might want to ask a student leader.Ask if youll have to pay for parking or if youll have to walk a million miles from a parking lot to your classe s. If you are very conservative or very liberal in your thinking, ask about the political and social climate. This is one of the things that could cause a feeling of discomfort or alienation down the road, so its not a silly question.

Matin luther King Juniors I have a dream speech Essay

Matin luther King Juniors I have a dream speech - Essay Example He is well-known worldwide for the speech â€Å"I have a dream†, which was delivered to a crowd of more than 200,000 Americans in 1963. This speech essentially refers to the importance of being given the same rights as other ethnic groups. Today, many people compare King’s â€Å"I have a dream† speech to the "We shall fight" speech, which was delivered by Winston Churchill during the Second World War when Britain suffered from nightly bombings conducted by the German Luftwaffe. Both speeches of the famous leaders sought to reassure their citizens that there was a day that will end the suffering and restore justice for all. Both speeches also called on citizens who were experiencing hardships to come together and fight for emancipation – in Churchill’s case, to protect the state from the Nazis, and in King’s case to fight against discrimination in American society. The â€Å"I have a dream† speech affected millions of citizens not only in the USA but abroad garnering sympathy for the African American cause. The effects of King’s speech on the international audience were immediate. King would make the cover of the ‘Times’ magazine in 1963 and receive the Nobel Peace Prize in 1964. In this particular speech, King sought to reassure disenfranchised people from different ethnicities and races, as well as religious minorities. He stated that all mistreated members of different communities could rise up to provide a united stand against injustice (Hansen 131). King was a unique man in that he believed that the proclaimed goals could be achieved without shedding of blood. This was quite an unusual stand at that time, especially when it came to politicians of the USA. It was hard to believe that King could succeed as most African and Asian nations seeking independence from their colonial masters around that time were engaged in violent riots and wars. King was quite courageous in openly criticizing the institution of segregation, which was usual at that time. In 1963, America was still a segregated society that allowed privileges for white people while African Americans were left to survive on little in the margins of society. Dr King was virtually risking his life by alluding, in his speech, to the fact that he hoped that in the nearest future, his children would not have to experience the segregation that had constantly marked his life. King used the power of emotions to appeal to citizens of different races, particularly those of the white race, to listen to their heart and common sense, to recall the words from the American constitution promising equal rights for all. In the speech, he expressed hope that time would come when his four children experience more freedom than him. By using children as a symbol of bright future, he was able to emotionally affect the white majority to see his point and understand his sorrow. There are no parents, black or white, who would like to s ee their children mistreated in any way or allowed fewer opportunities due to the color of their skin. King also used emotion in the description of African American life in the past and present. In one sentence of his speech he says, â€Å"One hundred years after President Lincoln set the slaves free, the Negro’s life remains wretchedly crippled by the chains of discrimination and segregation† (Hansen 134). By using words like â€Å"

Visual analysis of The Merode Altarpiece Essay Example | Topics and Well Written Essays - 750 words

Visual analysis of The Merode Altarpiece - Essay Example The Merode Altarpiece is a painting by Renaissance artist Robert Campin whose creation time is around 1427 to 1432. The painting was created in Tournai in the Netherlands, which is the artist’s place of origin but it is currently on display at the Metropolitan Museum in the United States (The Metropolitan Museum of Art). The painting is divided into three panels; the main panel shows the moment just before the annunciation of Mary. She is sitting on the floor reading a bible and is looking down. To her left is an angel she is not aware of, with an oval table separating them. A small figure of Jesus is flying towards Mary holding a crucifix. The right panel has Saint Joseph in a carpentry workshop where he is making mousetraps with a townscape appearing behind him in an open window. The right panel has two figures, assumingly the commissioners of the painting, called the donors waiting to go inside an open door (Barnet, Peter, & Nancy 125). This painting also goes by the name à ¢â‚¬Å"The Annunciation†, which is an event in the Christian Holy Bible in which a virgin by the name of Mary receives the news of her appointment to be the earthly mother of God’s son, Jesus.An angel from heaven visits her while she is at home and gives her the good news. The name itself also hints one on the purpose of the painting: Christian believers or cathedrals for devotional and aesthetic purposes commissioned altarpieces. It is therefore a religious artwork. The artist captures the human figures and specifically their faces with their expressions on, making the artwork more of a combination of portraits to make a composition. However, there are outdoor scenes appearing from the openings and windows in the backgrounds depicting cityscapes. The work therefore combines both landscape and portraiture although the portraiture aspect seems to dominate more. According to the Metropolitan Museum, The Merode Altarpiece measures 64.5 cm in length by 117.8 cm as an overall painting with a main panel of dimensions 64.1cm by 63.2 cm, and two identical side panels measuring 64.5cm by 27.3cm each. The width of the painting is slightly below two times the height therefore creating a rectangular (landscape) orientation of the work. The artist employs much use of rectangles, squares, and straight lines in vertical or horizontal movements that harmoniously blend in with the shape of the frame. For instance, in the middle panel where the figures are in a room and the wall and ceiling lines originate from the background and come to meet the frame, creating a view as if one is peering through a window or the wall is missing (Nici 243). The frames merge with most of the shapes rather than disagree with or break them. The Merode Altarpiece is oil on Oakwood. The style of creating workspace and framing is popular as panel art. Panel art is a technique of creating frames in the renaissance period where artists had carpenters make them wooden panels covered with clo th and plastered with gesso paste to create a smooth painting surface (D’Elia 19). The work is done in oil paints, which is another preference of most renaissance artists. During the renaissance period, the use of tempera colors was becoming unpopular as artists discovered that oil

Enthnography Essay Example | Topics and Well Written Essays - 1500 words

Enthnography - Essay Example If she does something that is considered bad, let her not deny it. Let her bare disgrace and let her endure when others speak evil or do evil to her†¦always let her seem to tremble and fear† (Rachel, 301). This audacious statement was put together by a respected man in ancient China whose opinion mattered in the courts of law and exerted great influence on the judge’s decision and judgment served to women. This is a brief peak into the setting of China about 2000 years ago. In ancient China, the girl child was always treated with contempt and referred to with disappointment by the men who would tower over them as though they were gods to be served and satisfied by the women. The women were more often than not looked upon as concubines and no woman would claim right, whether legally or morally to be the sole wife of one man. The men had every right to take to themselves as many women as he would to be his multiple wives. The married women would also fall in a hierarc hy based on simple factors as, the maid who was most favored by the master would come top of the list. Other bases would be the order in which they were married. To say that women in Chinese history were treated as animals would almost be an understatement since some of the practices were bordering evil. For example, one of the most common practices in ancient China was that of crippling women which started from their childhood where their feet would be bound (Rachel, 305). The arch of each foot would be deliberately broken and the foot tied to prevent it from growing. This would latter lead to a painful hobbling kind of motion for the women and their mobility would be limited to household chores. In the process of time, wealthy households and the non-aristocratic Chinese could not afford to have their women unable to work due to the crippling so they opted to keep them as slaves. They did jobs such as spinning clothes, processing tea and other labour intensive tasks in the home. Du ring these severe times of inequality, there were individuals who arose to show that women were not as useless as deemed and that they could exert a certain degree of influence. For example, in ancient history, the heir to the Chinese throne was taken by a young boy whose mother; ‘Empress Dowager’ was the true ruler (Rachel, 307). Another interesting area to note as the changes in tradition changed overtime, the role of arranging marriages was handed to an aunt or older female relatives. They decided which families would be allied by marriage and who would pay the dowry to whom. In some regions of ancient China an interesting tradition was developed of having groups of 6 to 7 women who would be â€Å"sworn-sisters† and they would even develop their language and system of writing to help them communicate amongst themselves. On the onset of the 19th century, there was an outcry of discontentment amongst the Chinese people regarding the roles of the women. However, it was not until the short lived Chinese republic that there was significant progress in the fight for women rights. The rise of communists under the Mao caused a shift in the long held beliefs and traditions that degraded the Chinese people and they were willing to die for their beliefs and one of their goals was to erase the inequality between the men and women once and for all. In these times women worked outside their home, were educated and involved themselves in political matters (Rachel, 309). With the death of Mao the nation moved towards a

The positive and negative impacts of an IT application within an Essay

The positive and negative impacts of an IT application within an organisation - Essay Example BT Industries is a manufacturer of trendy home appliances such as coffee makers, small microwaves, toasters, and an automatic defroster for frozen food. Market share was expected to increase from 4% to 12% in a highly competitive market. Projections were a direct result of the proven ability of designers to successfully anticipate trends for the BT market segment as well as the ability of the manufacturing sector to translate those designs into easily manufactured items. Location The Head Office is in Boston, with four assembly plants in Los Angeles, Seattle, Miami and Boston. The company accounting function is centralized in Boston with remote terminals at all manufacturing plants. Systems analysis and programming staff are also based in Boston whilst each of the four plants have only a few applications programmers to ‘trouble shoot’ on site. Market Essence of marketing is aimed at the ‘Yuppie’ market where two-income families have made time more precious than money. For this market, the emphasis is on up-to-date styling and perceived quality for traditional appliances. It is the intention of BT Industries to keep the final design of its products as secret as possible especially from Far East Asian competitors. IT Systems 1.4.1 CAD/CAM system in Boston with communications links directly to assembly plants. The purpose of the system is to accelerate the design process of currently sold appliances from the inception idea to the actual manufactured product.

Family law Essay Example | Topics and Well Written Essays - 1500 words - 1

Family law - Essay Example The major thrust of new legislation introduced through the Children and Adoption Bill 2005 which is derived from the Family Act of 19963 is to promote parental cooperation in ensuring that the child has contact with both parents. However, allowing primary custodial care to one parent – traditionally the mother – has been viewed as a failure of the legal system to ensure the rights of fathers; â€Å"an exercise in absolute futility† for fathers, as stated by Justice Mamby in the case of D4. In many instances, the underlying hostility the parents feel for each other affects the contact arrangements for the children and creates conditions that are not beneficial for them.6 This is the reason why shared residence appears to offer a viable option whereby a child is able to maintain contact with both parents without their mutual animosity affecting the child’s emotional and psychosocial makeup. Moreover, the separated parents may be living with other partners and the facility of shared residence allows each parent to participate in the care of the child while also being able to carry on with their lives and putting the animosity of the former relationship behind them. As a result, shared residence may be viewed as a means to protect the children from the worst effects of separation and the welfare of children is of primary importance, especially as identified in the Children Act of 1989. The concept of shared residence could therefore offer a solution. A child of divorced parents has two homes, one with each parent, such that both parents are able to offer emotional and financial support. Family Courts have traditionally been guided in their decisions by the provisions of the Children Act of 1989, which states that in any provision or decision made by the Courts, â€Å"the child’s welfare shall be the Court’s paramount consideration.†7 Section 11(4) of the Children Act of 1989

Parties and Pretrial Procedures Assignment Example | Topics and Well Written Essays - 750 words

Parties and Pretrial Procedures - Assignment Example On receiving complaints regarding a criminal act the investing authorities can initiate the investigation, and collect information. The next step involves the assessment of evidences, and analyzing the situation. For this purpose grand juries are called. The protocol of using grand jury for deciding criminal charges was abolished in 1948 in the United Kingdom; however, it is still in practice in the United States of America (Campbell, 1973). The function of a grand jury is to decide whether the act under question is chargeable as a crime or not. Cases that ask for the involvement of grand jury use it as a preliminary step for initiating the criminal proceeding. Grand jury is composed of sixteen to twenty three individuals. Prosecutors summon grand jury for testing their case. They collect all the evidences from the investigating authorities, and then present their case in front of the jury. Trials involving grand jury does not have any lawyer, except the prosecutor, the indictment of charges does not require unanimous decision; rather a super majority of 2/3 or 3/4 is enough to charge indictment. Decisions made by the grand jury are of basic nature, they solve the question of law, and they decide whether the defendant is eligible fo r being charged with conviction or not. During the trial the role of the prosecutor is to present all the available information to the jury, and explaining the injunctions of law. After viewing the available information, and the cited act, the jury decides, whether to call for a court proceeding or not. In all this process there is no involvement from the defendant’s side. The grand jury deals with the case keeping the prevalent culture and customs of their society (Antell, 1965). If the indictment has been approved warrants are released for the arrest of the convicted. After the arrest of the convict, the case is reviewed by the district attorney, who has the authority to discard the case on unavailability of

Family law Essay Example | Topics and Well Written Essays - 1500 words - 1

Family law - Essay Example The major thrust of new legislation introduced through the Children and Adoption Bill 2005 which is derived from the Family Act of 19963 is to promote parental cooperation in ensuring that the child has contact with both parents. However, allowing primary custodial care to one parent – traditionally the mother – has been viewed as a failure of the legal system to ensure the rights of fathers; â€Å"an exercise in absolute futility† for fathers, as stated by Justice Mamby in the case of D4. In many instances, the underlying hostility the parents feel for each other affects the contact arrangements for the children and creates conditions that are not beneficial for them.6 This is the reason why shared residence appears to offer a viable option whereby a child is able to maintain contact with both parents without their mutual animosity affecting the child’s emotional and psychosocial makeup. Moreover, the separated parents may be living with other partners and the facility of shared residence allows each parent to participate in the care of the child while also being able to carry on with their lives and putting the animosity of the former relationship behind them. As a result, shared residence may be viewed as a means to protect the children from the worst effects of separation and the welfare of children is of primary importance, especially as identified in the Children Act of 1989. The concept of shared residence could therefore offer a solution. A child of divorced parents has two homes, one with each parent, such that both parents are able to offer emotional and financial support. Family Courts have traditionally been guided in their decisions by the provisions of the Children Act of 1989, which states that in any provision or decision made by the Courts, â€Å"the child’s welfare shall be the Court’s paramount consideration.†7 Section 11(4) of the Children Act of 1989

High School vs. College Essay Example for Free

High School vs. College Essay High school and college are similar in some ways and different in a lot of ways. They are similar in such ways that you still have to go to class, do class work, home work, take test, and study hard. They are different in such ways that we can have cell phones in class, walk out of class, wear anything to class, and the thing that sets it off is living on campus. I don’t know if my college experience will match up to my high school experience but, we shall see. I will compare and contrast high school and college. I use to drive to high school. For some reason South Carolina State University will not let freshman drive their first semester. I use to drive ten to fifteen minutes to get to school, now it’s about one hour and a half. So instead of doing that everything, I stay on campus and walk to class. I must admit that I didn’t think it would be difficult at first but, it is. I hate relying on someone else to take me to Wal-Mart. That’s one thing that’s different about the two subjects at hand. And the way they’re similar is that I didn’t drive as a freshman in high school. In high school, there was a lot of freedom. We got to change classes on our own, the classes were mixed up with students in different grades, and we didn’t have to walk in a single or double filed line. In college, you don’t even have to go to class. Although it would be wise, too. In high school if you miss a day in class, the teacher would call home. In college, they don’t call anybody, not unless their name is Mrs. Pinson. In high school, I lived with my mother. In college, I live with a roommate. Technically , I’m out on my own but, my mother is paying for my education and family is putting money in my pockets. I was always curious to know what it’d be like to get out on my own. I must say, I’m one step closer. Now that I’m in college, I wish we stayed in dorms in high school. If that would have went down in high school though, there probably wouldn’t be any need to go off to far away colleges. So to sum everything up, I can’t drive, there is a lot more freedom, and I don’t stay in my mother’s house any more. I drove, had freedom but not this much, and I stayed with my mother in high school. Some things that were similar are the work, tests, quizzes, and studying. Those are some things that I chose to compare and contrast on high school versus college.

African Trypanosomiasis Sleeping Sickness Biology Essay

African Trypanosomiasis Sleeping Sickness Biology Essay African trypanosomiasis also known as sleeping sickness is a wide spread parasitic disease (disease caused by organism that lives in or on another from which it obtains nourishment) that can be fatal if not treated. It is estimated by the World Health Organisation (WHO) that it has 450 000 cases each year, however in the past there have epidemics (a rapid spread or increase) such as between 1896 and 1906 where it is believed that 300 000 to 500 000 died from the disease. [1] African trypanosomiasis is common in the sub-Saharan region near rivers, lakes, in gallery forests and in Savannahs where the large brown tsetse flies are present. It occurs in these remote rural areas because the health systems are weak and because most of these areas depend on agriculture, fishing, animal husbandry or hunting so they are exposed to the tsetse flies. [2]The disease has been present in Africa for a minimum of 14 centuries with millions of people being affected by it. As you can see below (in figure 1) the distribution of trypanosomiasis in Africa comprises currently an area of 8 million km2 between 14 degrees North and 20 degrees South latitude. tryp_map.gif [Fig. 1] Distribution of human African trypanosomiasis. http://www.who.int/tdrold/dw/images/legend5.gifEpidemic http://www.who.int/tdrold/dw/images/legend6.gifHigh endemicity http://www.who.int/tdrold/dw/images/legend4.gifLow endemicity http://www.who.int/tdrold/dw/images/legend7.gifAt risk http://www.who.int/tdrold/dw/images/legend3.gifAbsence of the disease   As well as African trypanosomiasis also occurs in South America it is called the American trypanosomiasis or the Chagas disease however the organism causing that disease is different to the Tsetse flies. African trypanosomiasis is however more common than the South American version and it is estimated that around 50,000 to 70,000 people are currently infected with it and around 48,000 people died from it in 2008. [3] If, like most diseases, African Trypanosomiasis is diagnosed early there is a high chance of survival. There are no effective vaccines, and the drugs used to treat this disease are often toxic and usually have many side effects. Untreated cases have a 100 percent  mortality rate. [4] The extent of African Trypanosomiasis is shown more clearly when compared to other diseases and during epidemic periods prevalence reached 50% in several villages in the Democratic Republic of Congo, Angola and Southern Sudan. Sleeping sickness was the first or second greatest cause of mortality in those communities, ahead of even HIV/AIDS. [5] There are two types of African trypanosomiasis which are common in humans. The first of the two sub species is trypanosomiasis brucei gambiense which causes a slow chronic trypanosomiasis in humans. This mostly occurs in central and western Africa, where humans are thought to be the primary target. The second is T. brucei rhodesiense and this causes a rapid onset of trypanosomiasis in humans and this is most common in southern and eastern Africa, where animals are the primary target. Tsetse flies are large flies which can be easily misinterpreted for a housefly but can be distinguished by various characteristics. These flies cause human sleeping sickness and animal trypanosomiasis (or nagana) as well as other diseases and its estimated it kills around 250,000 to 300,000 people a year. Tsetse flies are multivoltine (they have more than 2 generations per year) and there are 23 species of this fly existent today. Tsetse flies include all the species in the genus Glossina, which are generally placed in their own family, the Glossinidae. [6] AfrTryp_LifeCycle.gif[Fig. 2] [1] When a tsetse fly bites it takes blood from a human or animal host. [2] If the tsetse fly is infected it injects metacyclic trypomastigotes into skin tissue and the parasites enter the lymphatic system (part of the immune system) and pass into the bloodstream. Inside the host, they transform into bloodstream trypomastigotes and are carried to other parts of the body. [3] After this bloodstream trypomastigotes reach other blood fluids such as lymph, spinal fluid and continue the replication by binary fission (Asexual reproduction where parent cells divide into two equal parts.). [4/5] The entire life cycle of African Trypanosomes is in extracellular (outside the cells) stages. A tsetse fly becomes infected with bloodstream trypomastigotes when taking a blood meal on an infected host . [6] In the tsetse flies midgut (the mid section of the digestive tract), the parasites generate a cycle of trypomastigotes, they then multiply by binary fission and leave the midgut. [7] Thereafter the parasites transform into epimastigotes (a developmental stage in trypanosomes) [8] The epimastigotes reach the flys salivary glands and continue multiplication by binary fission . This cycle in the fly takes approximately 3 weeks to occur. http://www.icp.ucl.ac.be/~opperd/parasites/images/dia3.jpg[Fig.3] This picture shows an African male in the late stage of African trypanosomiasis Describe the biological processes involved in producing solutions to the problem You can spot African trypanosomiasis early if the following symptoms occur, and treating the disease early increases the chances of survival. Symptoms of sleeping sickness begin with fever, headaches, and joint pains. If untreated, the disease slowly overcomes the immune defences of the infected person, and symptoms spread to anaemia, cardiovascular and kidney disorders. The disease then enters a neurological phase when the parasite passes through the blood-brain barrier (BBB). The symptoms of the second phase is what gives the disease its name, sleeping sickness, besides confusion and reduced coordination, the sleep cycle is disturbed with a period of lower level consciousness and periods of inability to sleep progressing to daytime drowsiness and night-time insomnia. Without treatment, the disease is fatal, with progressive mental deterioration leading to coma and death. Damage caused in the neurological phase can be irreversible. [7] Stage 1 illness: 2 to 3 weeks later, Stage 1 disease develops as a result of the protozoa being carried through the blood and lymph circulation of the host. This phase of the illness is represented by a high fever that falls and rises again, also irritating rashes, and headaches may occur. The Gambiense form, in particular, includes extreme swelling of lymph tissue, with enlargement of both the spleen and liver, and greatly swollen lymph nodes. During this stage, the heart may be affected by a severe inflammatory reaction, particularly when the infection is caused by the Rhodesiense variety of trypanosomiasis. These symptoms usually occur because of our immune system trying to defeat the invading organism; this is because of the increasing activity of our cells damaging organs and tissues. This may cause some blood vessels to leak and as a result of this the protozoa may spread further around the body. The immune system responds so violently because the trypanosomes survive so well by quickly changing specific markers, which are the outer coats of unique proteins. These proteins stimulate the hosts immune system to produce immune cells which will specifically target the marker, allowing quick destruction of those cells bearing the markers. Trypanosomes, however, are able to express new markers at such a high rate of change that the hosts immune system is constantly trying to catch up. Stage 2 illness This involves the nervous system, especially Gambiense sleeping sickness, which has a phase in which the symptoms involve the brain. These symptoms are that the patients speech becomes slurred, mental processes slow, and the patient sits and stares for long periods of time, or sleeps. Other symptoms resemble Parkinsons disease, including imbalance when walking, slow and shuffling gait, trembling of the limbs, involuntary movements, muscle tightness, and increasing mental confusion. Untreated, these symptoms could eventually lead to coma and then to death. [8] There are various treatments for the disease but it depends on the how bad the disease has got and what stage it is at. Suramin, eflornithine, pentamidine, and several drugs which contain arsenic (a chemical which in higher doses is highly poisonous to humans), are all effective anti-trypanosomal agents. When the disease is in its early stages it is easier to control and its treatments are the most effective, the least toxic, so the earlier the identification of the disease, the better the prospect of a cure. At the second stage the treatments depend on drugs that can cross the blood and the brain, to reach the parasite, however these drugs are more toxic and therefore carry a risk with them. There are four drugs that have been registered for the treatment of sleeping sickness which are; pentamidine, melarsoprol, eflornithine and suramin. If the disease is diagnosed early, the chances of cure are high. The type of treatment depends on the phase of the disease: initial or neurological. During which the second stage of the trypanosome parasites reside in the cerebrospinal fluid (CSF) so success in the latter phase depends on having a drug that can cross the blood-brain barrier (BBB) to reach the parasite. Four drugs have been used until now. Without treatment, sleeping sickness will lead to death. Unfortunately, however, those medications effective against the Trypanosoma brucei complex protozoa all have significant potential side effects for the patient. An external file that holds a picture, illustration, etc. Object name is AFHS0604-0223Fig1.jpg Object name is AFHS0604-0223Fig1.jpg [Fig 4] Sleeping sickness in South-Eastern Uganda from 1905- 2001 As you can see in figure 5 there were a high number of deaths of people from Trypanosomiasis from 1905-1915 but even thought the number decreases there have still been a lot of cases in this small region in the past 30 years and the number has been predicted to increase from The First Stage Treatment Suramin: Suramin is a colourless derivative. The development of suramin followed observations that a number substances. Suramin has six negative charges at physiological pH, thereby preventing its diffusion across cell membranes and it could possibly be used against late stage trypanosomiasis because it does not cross the BBB. Suramin is generally considered the drug of choice for the early stages of human African trypanosomiasis, especially T. b. rhodesiense infections. Because of the size and charge of suramin it makes it unsuitable to have a specific transporter. Suramin easily binds to many proteins. At attainable levels, more than 75% of suramin is bound to proteins, which include low-density lipoproteins (LDL). LDL and transferin are taken up through a receptor-mediated endocytosis and suramin enters the parasite specifically found to LDL. Accumulation of the drug in trypanosomes is relatively slow. In some studies, suramin has interfered with the metabolism of trypanosomes in different ways: It hampers the receptor mediated uptake of LDL, the carrier of cholesterol which is required for parasite growth Suramin, which enters via receptor mediated endocytosis in association with LDL, is most likely to accumulate inside the lysosome. Several of the enzymes encountered by suramin on its way from the extracellular fluid to the secondary lysosomes become inhibited by suramin. Many glycolytic enzymes located inside the glycosome on the African trypanosome carry a high positive charge, and therefore are all inhibited by micro molar levels of suramin. Second Stage Treatment Eflornithine: Eflornithine is an off-white, odourless, powder; the compound is freely soluble in water and sparingly soluble in ethanol. It is used mainly as a backup drug for melarsoprol but now in places such as Uganda it has become the first line treatment for sleeping sickness. Adverse drug reactions during eflornithine therapy are frequent. Their occurrence and intensity increase with the duration of treatment and the severity of the general condition of the patient. Generally, adverse reactions to eflornithine are reversible after the end of treatment. Trypanosomes are more susceptible to the drug than human cells, possibly due to the slow turnover of the ODC enzyme (which is key in the biosynthesis of polyamines) in T. b. gambiense. Eflornithine can effectively inhibit ODC activity and use the supply of polyamines in trypanosomes, which bring them into a motionless state that makes them vulnerable to the hosts immune attack. Therefore, a sufficiently active immune system is required to achieve a cure. Additionally, eflornithine induces the differentiation of thin forms to larger forms which do not divide anymore and therefore become accessible to the immune system. [9] It was found in a study that the effectiveness of eflornithine was 98.7% on its patients which is a high cure rate. Explain how the processes used are appropriate in terms of producing effective solutions to address the problem As you can see a total of 6 patients died, 5 of them on the 14 day course therefore the 7 day course seems to be much more effective. The 7 day course seems to be cause less adverse events in general then the 14 day course. [Fig. 5] However concluding figure 6 we can see that the probability of cure is higher in the 14 day regime then the 7 day regime. So even though there are some side effects of the 14 day regime still has a greater chance of curing the disease.[Fig. 6] F1_medium.gif [Fig. 7] A total of 103 patients with second-stage disease were enrolled. Cure rates were 94.1% for the eflornithine group and 96.2% for the nifurtimox-eflornithine group. Drug reactions were frequent in both arms, and severe reactions affected 25.5% of patients in the eflornithine group and 9.6% of those in the nifurtimox-eflornithine group, resulting in 2 and 1 treatment suspensions, respectively. There was 1 death in the eflornithine arm and no deaths in the nifurtimox-eflornithine arm. [10] The nifurtimox-eflornithine combination appears to be a promising first-line therapy for second-stage sleeping sickness. [10] F1_medium.gif [Fig 8] shows the probability of an event free survival among 1055 patients; they were treated with eflornithine for newly diagnosed second stage human African trypanosomiasis in Ibba, Southern Sudan. 1756-3305-1-3-3.jpg[Fig. 9] The combined efforts of chemotherapy, systematic case detection and vector control led to a dramatic reduction in the incidence of sleeping sickness at the beginning of the 1960s as shown in figure 2. The grey bars represent the number of cases whilst the line graph shows the population screened. Identify 2 implications of the solution encountered Suramin As suramin can only be injected it causes problems as African Trypanosomiasis can be spread easily from the needles not bring cleaned properly. If the patients who dont have the disease are injecting with the same unclean needle as people who are diagnosed this would result in the non-infected patients being infected. Further problems of suramin are that it has many side effects which include abdominal pain, diarrhoea, metallic taste and joint pain. Less common side effects are loss of vision and swelling around eyes. It can even rarely cause fainting and death. The advantages are that many of these side effects can be stopped by using a small sample dose, 100 mg IV, to test any toxic reactions of the patients. Eflornithine The route of application makes financial difficulties due to the workload and the additional material needed. A recently investigated abbreviated course of 7 days was found to cause a high relapse rate for the treatment of new cases. The superior outcome reported for the treatment of relapses still has to be confirmed, since there were a very small number of participants in the study. If there was an oral form for the treatment of sleeping sickness it would be more appropriate as it would be cheaper and less time consuming. In a study the average cost of eflornithine per patient being 552.3 USD and the cost per patients life saved averaging 559.8 USD. [10] Eflornithine also has side effects which include acne stinging skin; headache; dry skin; itching; erythema (redness); dyspepsia(upset stomach or indigestion); alopecia Fortunately there are advantages of this drug as efforts for the developments of an oral form of eflornithine are currently being made under the World Health Organisation/World Bank special programme for research and training in tropical diseases. This drug is generally better tolerated than the first line drug melarsoprol. It was found in a study that the effectiveness of eflornithine was 98.7% on its patients which is very high and therefore if the illness is treated within its late stages, stage 2, the chances of survival are still high. Evaluate the benefits and risks to humans, organisms and the environment Benefits: The side effects of Suramin can be stopped by using a small sample dose, 100 mg IV, to test any toxic reactions of the patients, so this means it could An oral form of eflornithine is currently being made under the World Health Organisation/World Bank special programme for research and training in tropical diseases. This would lead to cheaper costs of to treat a patient; therefore more people can be treated and cured. Effectiveness of eflornithine is 98.7% on its patients which is very high and therefore if the illness is treated within its late stages, stage 2, the chances of survival are still high, so a lot less people die when using the treatment. Disadvantges: The average cost of eflornithine per patient being 552.3 USD is far too high to cure most of the people especially because the treatment mainly depends on donated money as the government of the Third World countries are too poor to afford the treatment, so by using this lots of people may never be treated and therefore there may be a rise in the death rate. As the treatment of patients decreases, if people donate less, the number of deaths from the disease will increase. Further disadvantages of the treatments are that they both carry many side effects, even though some of these side effects arent major, the lack of treatments in these poor countries could result in a gradual decrease in health over time. Also some of the side effects and over doses could lead to death or serious illnesses so it is important to administer the drugs carefully and correctly as the end result could be fatal. Discuss alternative views or solutions for the problem encountered Pentamidine: Pentamidine can be used instead of suramin for a first stage treatment of trypanosomiasis. It is medication with a very slow rate of diffusion across biological membranes and it only treats the T.B.G. form of African sleeping sickness in the first stage. It could be injected or inhaled by the patient. Because of poor GI absorption, the drug is administered IV/IM and is strongly bound to tissues, including spleen, liver, and kidney. Clinical improvement usually noted within 24 h of injection. Reported to have a >90% cure rate. Pentamidine does not penetrate the blood-brain barrier effectively and, therefore, does not treat CNS infection. [9] Fifty-eight patients in the early-late stage (early central nervous system involvement) of Trypanosoma brucei gambiense trypanosomiasis were treated with pentamidine and divided into four groups according to cerebrospinal fluid (CSF) indicators: white blood cell (WBC) count, protein level (CSF protein), and the presence or absence of trypanosomes. Group 1 consisted of eight patients with normal CSF WBC counts and CSF protein levels and trypanosomes in the CSF. Group 2 consisted of nine patients with elevated CSF WBC counts, normal level of CSF protein, and trypanosomes in the CSF. Group 3 consisted of 31 patients with high CSF WBC counts, normal CSF protein levels, but no trypanosomes in the CSF. Group 4 consisted of 10 patients with normal CSF WBC counts and CSF protein levels and trypanosomes demonstrated by CSF culture. Post-treatment follow-up of all patients for at least one year revealed three relapses. There were two deaths from diseases unrelated to trypanosomiasis or to the treatment protocol. Of these patients, 52 were followed for more than two years, the time necessary to confirm a complete cure, indicating a cure rate of 94%. Pentamidine is therefore effective in treating the early-late stage of T. b. gambiense trypanosomiasis, and is comparable with melarsoprol or eflornithine in terms of its tolerance and availability. [11] Side effects: Shortness of breath; closing of the throat; hives; swelling of the lips, face, or tongue; rash; or faintin;, bleeding or bruising; blurred vision; chest pain or irregular heart beat; chills; difficulty breathing dizziness, fainting spells or excessive tiredness; drastic appetite changes; mouth ulcers severe stomach pain; severe headache; seizureshttp://bryanking.net/wp-content/uploads/2009/01/hives.jpg [Fig 10] This picture shows hives which is a common side effect of pentamidine Melarsoprol: Melarsoprol contains an arsenic element with a reactive arsenoxide group. The presence of the arsenoxide enables the ability of lipid solubility and this allows passage across the BBB. Apart from its transport function, the arsenoxide group mediates in the killing of the parasites in the bodily fluid; CSF (Cerebrospinal fluid). Modification of the melarsoprol parent ring to generate other analogous compounds can have a significant impact on its trypanocidal efficacy. The trivalent arsenicals; melarsoprol, melarsen oxide and phenylarsen are highly active with a minimum inhibitory concentration. Usually the transport of melarsoprol into the trypanosome parasite is accomplished by purine tranporters. Purine transport is highly developed in trypanosomes as they do not synthesize nucleic acids and must directly acquire them from their hosts. Resistance The failure of melarsoprol to cure 10% of the late stage sleeping sickness patients possibly relates to the fact that these individuals accumulate levels of the drug in the brain. However, one study has indicated that the levels of drug are similar in the CSF of relapsing and non-relapsing patients, so parasites at other extravascular sites may be key to the treatment failure. In some regions, treatment failures have reached high levels up to 30%. Parasites retrieved from the patients with these treatment failures were less responsive to melarsoprol than parasites isolated from other foci. This clearly points to some form of mutation towards resistance. Indeed arsenic refractory parasites do possess an unusual amino purine transporter which accumulates melarsoprol and the loss of this transporter in the parasite leads to drug resistance. T. brucei contains several of the purine nucleoside transporter activities. [9] Melarsoprol is a good alternative and is used as the first line drug against Human African Trypanosomiasis (HAT) in many countries. This is because the drug has longer intervals between when the dosages should be taken so it requires fewer resources and is therefore cheaper. However melarsoprol is a highly dangerous treatment, only administered by injection under the supervision of a physician. It causes a range of side effects, among them convulsions, fever, unconsciousness etc. It is fatal in and of itself in approx. 10% of the cases. Meanwhile eflornithine is a modern and far less dangerous treatment for HAT but it is expensive not widely available in the market and the money for supplies are usually dependable on donations. Melarsoprol is a good alternative and is used as the first line drug against Human African Trypanosomiasis (HAT) in many countries. This is because the drug has longer intervals between when the dosages should be taken so it requires fewer resources and is therefore cheaper. However melarsoprol is a highly dangerous treatment, only administered by injection under the supervision of a physician. It causes a range of side effects, among them convulsions, fever, unconsciousness etc. It is fatal in and of itself in approx. 10% of the cases. Meanwhile eflornithine is a modern and far less dangerous treatment for HAT but it is expensive not widely available in the market and the money for supplies are usually dependable on donations.